Hauv ntiaj teb kev tu tawv nqaij, niacinamide zoo li tus neeg ncaws pob thoob plaws ntiaj teb, kov yeej lub siab ntawm cov neeg nyiam kev zoo nkauj suav nrog nws ntau yam teebmeem. Niaj hnub no, cia peb nthuav tawm cov ntaub thaiv tsis meej ntawm "lub hnub qub saib xyuas tawv nqaij" thiab tshawb nrhiav nws cov kev paub tsis meej thiab cov kev siv tswv yim ua ke.
1, Kev txiav txim siab ntawm nicotinamide
Niacinamideyog ib daim ntawv ntawm vitamin B3, tshuaj hu ua pyridine-3-carboxamide. Nws cov qauv molecular muaj lub nplhaib pyridine thiab ib pab pawg amide, uas ua rau nws muaj kev ruaj ntseg zoo thiab kev ua haujlwm lom neeg.
Cov txheej txheem ntawm kev ua hauv daim tawv nqaij feem ntau suav nrog inhibiting melanin hloov mus, txhim kho daim tawv nqaij barrier muaj nuj nqi, thiab tswj sebum secretion. Kev tshawb fawb tau pom tias nicotinamide tuaj yeem ua rau muaj txiaj ntsig zoo ntawm ceramides thiab fatty acids, txhim kho kev ncaj ncees ntawm stratum corneum.
Lub bioavailability yog tus yuam sij rau kev ua tau zoo ntawm nicotinamide. Nws muaj qhov hnyav me me (122.12 g / mol), muaj zog dej solubility, thiab tuaj yeem nkag mus tob rau hauv cov epidermis. Cov ntaub ntawv sim qhia tau hais tias bioavailability ntawm tshuaj pleev nicotinamide tuaj yeem ncav cuag 60%.
2, Ntau yam teebmeem ntawm nicotinamide
Hauv kev ua kom dawb, nicotinamide ua tiav cov tawv nqaij zoo ib yam los ntawm inhibiting kev hloov ntawm melanosomes rau keratinocytes. Kev sim tshuaj ntsuam xyuas tau pom tias tom qab siv cov khoom uas muaj 5% niacinamide rau 8 lub lis piam, thaj tsam ntawm pigmentation txo qis los ntawm 35%.
Rau kev tswj roj thiab tshem tawm pob txuv, niacinamide tuaj yeem tswj cov qog sebaceous thiab txo qis sebum secretion. Kev tshawb fawb tau lees paub tias tom qab siv cov khoom uas muaj 2% niacinamide rau 4 lub lis piam, sebum secretion txo los ntawm 25% thiab cov pob txuv txo los ntawm 40%.
Hais txog kev tiv thaiv kev laus, niacinamide tuaj yeem txhawb nqa collagen synthesis thiab txhim kho daim tawv nqaij elasticity. Kev sim tau pom tias siv cov khoom uas muaj 5% niacinamide rau 12 lub lis piam txo cov kab mob ntawm daim tawv nqaij los ntawm 20% thiab nce elasticity los ntawm 30%.
Kev kho qhov teeb meem muaj nuj nqi yog lwm qhov zoo dua ntawm niacinamide. Nws tuaj yeem txhawb cov synthesis ntawm ceramides thiab txhim kho daim tawv nqaij lub peev xwm khaws dej. Tom qab siv ib yam khoom uas muaj 5% niacinamide rau 2 lub lis piam, qhov transdermal ya raws ntawm daim tawv nqaij poob 40%.
3 、 Kev siv lub tswv yim ntawm nicotinamide
Thaum xaiv cov khoom uas muaj niacinamide, yuav tsum tau them nyiaj mloog mus rau concentration thiab formula. 2% -5% yog qhov muaj kev nyab xeeb thiab muaj txiaj ntsig zoo, thiab cov concentration ntau dhau tuaj yeem ua rau khaus. Nws raug nquahu kom pib nrog qis concentrations thiab maj mam tsim kom muaj kev kam rau siab.
Cov lus qhia siv suav nrog: siv thaum sawv ntxov thiab yav tsaus ntuj, ua ke nrog cov tshuaj antioxidants (xws li vitamin C), thiab xyuam xim tiv thaiv lub hnub. Kev tshawb fawb tau pom tias kev sib xyaw ntawm niacinamide thiab vitamin C tuaj yeem ua rau muaj txiaj ntsig zoo.
Ceeb toom: Kev khaus me ntsis tuaj yeem tshwm sim thaum pib siv, nws raug nquahu kom ua qhov kev sim hauv zos ua ntej. Tsis txhob siv cov khoom uas muaj acidity ntau dhau los txo qhov kev ruaj ntseg ntawm niacinamide.
Kev tshawb pom thiab kev siv nicotinamide tau coj cov kev hloov pauv hloov mus rau thaj chaw kho tawv nqaij. Los ntawm kev ua kom dawb thiab qhov muag pom kev rau cov roj tswj thiab kev tiv thaiv pob txuv, los ntawm kev tiv thaiv kev laus mus rau kev kho qhov teeb meem, cov khoom xyaw ntau yam no tau hloov txoj kev uas peb tu peb cov tawv nqaij. Los ntawm kev nkag siab txog kev tshawb fawb thiab kev siv kom raug, peb tuaj yeem siv tag nrho cov txiaj ntsig ntawm niacinamide kom ua tiav cov tawv nqaij noj qab haus huv thiab zoo nkauj. Cia peb txuas ntxiv tshawb nrhiav qhov tsis meej ntawm kev tu tawv nqaij thiab txuas ntxiv mus tom ntej ntawm txoj kev nrhiav kev zoo nkauj.
Post lub sij hawm: Mar-19-2025
