Panthenol yog ib qho derivative ntawm vitamin B5, tseem hu ua retinol B5. Vitamin B5, tseem hu ua pantothenic acid, muaj cov khoom tsis ruaj khov thiab yooj yim cuam tshuam los ntawm qhov kub thiab txias, ua rau txo qis hauv nws cov bioavailability. Yog li ntawd, nws cov precursor, panthenol, feem ntau yog siv rau hauv cov tshuaj pleev ib ce.
Piv nrog rau cov vitamin B5 / pantothenic acid, panthenol muaj cov khoom ruaj khov dua nrog qhov hnyav molecular ntawm tsuas yog 205. Nws tuaj yeem nkag mus rau hauv stratum corneum tau zoo thiab hloov mus rau hauv vitamin B5, uas yog ib feem tseem ceeb ntawm lub cev metabolism thiab ib qho tseem ceeb raw khoom. rau synthesis ntawm coenzyme A.CoenzymeA yog ib qho tseem ceeb hauv ntau txoj hauv kev enzyme hauv lub cev. Nws koom nrog hauv cellular zog metabolism, muab lub zog rau lub cev lub neej kev ua ub no. Tsis tas li ntawd, nws kuj koom nrog hauv cov metabolism ntawm ntau yam tseem ceeb hauv daim tawv nqaij, xws li cov roj (cholesterol), fatty acids, thiab sphingolipids synthesis.
Kev siv tshuaj pleev xim panthenol rau ntawm daim tawv nqaij pib xyoo 1944 thiab muaj keeb kwm ntau dua 70 xyoo. Nws yog tsuas yog siv hauv tshuaj pleev ib ce rau moisturizing, soothing, thiab kho lub hom phiaj.
Lub luag haujlwm tseem ceeb tshaj plaws
Moisturizingthiab txhim kho cov teeb meem
Panthenol nws tus kheej muaj lub luag haujlwm ntawm kev nqus dej noo thiab khaws cia, thaum txhawb lipid synthesis, ua kom cov kua dej ntawm lipid molecules thiab keratin microfilaments, txhim kho qhov chaw nruj ntawm keratinocytes, thiab pab tswj kev noj qab haus huv ntawm daim tawv nqaij barrier muaj nuj nqi. Nws yuav tsum tau muab sau tseg tias nyob rau hauv thiaj li yuav panthenol los txhim kho cov nyhuv barrier, lub concentration yuav tsum yog 1% los yog siab dua, txwv tsis pub 0.5% tsuas yog ib tug moisturizing nyhuv.
Soothing
Cov nyhuv soothing ntawm panthenol feem ntau yog los ntawm ob yam: ① tiv thaiv oxidative kev nyuaj siab puas tsuaj ② txo cov inflammatory teb
① Panthenol tuaj yeem txo qis kev tsim cov pa oxygen reactive nyob rau hauv daim tawv nqaij hlwb, thaum upregulating ntawm daim tawv nqaij nws tus kheej antioxidant mechanism, nrog rau inducing cov tawv nqaij hlwb kom nthuav tawm ntau antioxidant yam - heme oxygenase-1 (HO-1), yog li txhim kho daim tawv nqaij antioxidant muaj peev xwm Pantothenic acid. tuaj yeem txo cov lus teb inflammatory. Tom qab stimulating keratinocytes nrog capsaicin, tso tawm ntawm inflammatory yam tseem ceeb IL-6 thiab IL-8 ho nce. Txawm li cas los xij, tom qab kev kho mob nrog pantothenic acid, kev tso tawm ntawm cov kab mob inflammatory tuaj yeem cuam tshuam, yog li txo qis cov lus teb thiab txo qhov mob.
Txhawb nqakho
Thaum cov concentration ntawm panthenol nyob nruab nrab ntawm 2% thiab 5%, nws tuaj yeem txhawb kev tsim kho ntawm cov tawv nqaij puas ntawm tib neeg. Tom qab kho cov qauv kev raug mob laser nrog panthenol, kev qhia ntawm Ki67, ib qho cim rau keratinocyte proliferation, nce, qhia tau hais tias ntau keratinocytes nkag mus rau hauv lub xeev proliferative thiab txhawb epidermal regeneration. Lub caij no, qhov kev qhia ntawm filaggrin, ib qho tseem ceeb cim rau keratinocyte sib txawv thiab teeb meem muaj nuj nqi, kuj nce, qhia txog kev txhawb nqa ntawm daim tawv nqaij barrier kho. Ib txoj kev tshawb fawb tshiab hauv xyoo 2019 tau pom tias panthenol txhawb kev kho qhov txhab sai dua li cov roj ntxhia thiab tuaj yeem txhim kho qhov caws pliav.
Post lub sij hawm: Aug-30-2024
